You Can Change Your DNA. Octopus does change it s RNA.

17.02.2020 21:02

Changing DNA Through Intention

HELA ARTIKELN FINNS  HÄR. 
 

The power of intentional thoughts and emotions goes beyond theory at the HeartMath Institute. In a study, researchers have tested this idea and proven its veracity.

HeartMath researchers have gone so far as to show that physical aspects of DNA strands could be influenced by human intention. The article, Modulation of DNA Conformation by Heart-Focused Intention – McCraty, Atkinson, Tomasino, 2003 – describes experiments that achieved such results.

For example, an individual holding three DNA samples was directed to generate heart coherence – a beneficial state of mental, emotional and physical balance and harmony – with the aid of a HeartMath technique that utilizes heart breathing and intentional positive emotions. The individual succeeded, as instructed, to intentionally and simultaniously unwind two of the DNA samples to different extents and leave the third unchanged.

“The results provide experimental evidence to support the hypothesis that aspects of the DNA molecule can be altered through intentionality,” the article states. “The data indicate that when individuals are in a heart-focused, loving state and in a more coherent mode of physiological functioning, they have a greater ability to alter the conformation of DNA.

“Individuals capable of generating high ratios of heart coherence were able to alter DNA conformation according to their intention. … Control group participants showed low ratios of heart coherence and were unable to intentionally alter the conformation of DNA.”

 

"...octopuses, along with some squid and cuttlefish species, routinely edit their RNA (ribonucleic acid) sequences to adapt to their environment.

In 2015, researchers discovered that the common squid has edited more than 60 percent of RNA in its nervous system. Those edits essentially changed its brain physiology, presumably to adapt to various temperature conditions in the ocean.

The team returned in 2017 with an even more startling finding - at least two species of octopus and one cuttlefish do the same thing on a regular basis. To draw evolutionary comparisons, they also looked at a nautilus and a gastropod slug, and found their RNA-editing prowess to be lacking.

"This shows that high levels of RNA editing is not generally a molluscan thing; it's an invention of the coleoid cephalopods," said co-lead researcher, Joshua Rosenthal of the US Marine Biological Laboratory.

The researchers analysed hundreds of thousands of RNA recording sites in these animals, who belong to the coleoid subclass of cephalopods. They found that clever RNA editing was especially common in the coleoid nervous system.

"I wonder if it has to do with their extremely developed brains," geneticist Kazuko Nishikura from the US Wistar Institute, who wasn't involved in the study, told Ed Yong at The Atlantic

 

It's true that coleoid cephalopods are exceptionally intelligent. There are countless riveting octopus escape artist stories out there, not to mention evidence of tool use, and that one eight-armed guy at a New Zealand aquarium who learned to photograph people. (Yes, really.)

So it's certainly a compelling hypothesis that octopus smarts might come from their unconventionally high reliance on RNA edits to keep the brain going.

"There is something fundamentally different going on in these cephalopods," said Rosenthal.

But it's not just that these animals are adept at fixing up their RNA as needed - the team found that this ability came with a distinct evolutionary tradeoff, which sets them apart from the rest of the animal world.

In terms of run-of-the-mill genomic evolution (the one that uses genetic mutations, as mentioned above), coleoids have been evolving really, really slowly. The researchers claimed that this has been a necessary sacrifice - if you find a mechanism that helps you survive, just keep using it.

"The conclusion here is that in order to maintain this flexibility to edit RNA, the coleoids have had to give up the ability to evolve in the surrounding regions - a lot,"

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